Hacking the ribosome to map virus-host associations



Image by Junfeng Liu & Mart Krupovic

Viruses and the viral world

Viruses are microscopical biological entities with extraordinary success. Their ancient origin, long evolutionary history with hosts, and high mutation rates result in an unmatched diversity. Although viruses are able to infect almost every organism, are ubiquitous and play fundamental roles in the ecosystems, our knowledge of the viral world is limited by cultural and technical aspects. 

A better understanding of the viral world is essential, scientifically exciting, and is the main driver of the research embedded in the VirHoX project.
 
This project has received funding from the European Union’s Horizon Europe research and innovation programme under grant agreement No 101186013. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or European Innovation Council and SMEs Executive Agency (EISMEA). Neither the European Union nor the granting authority can be held responsible for them.

Our IDEA

Hacking the ribosome to map virus-host associations

01

The problem

High-throughput sequencing and metagenomics have enhanced our understanding of viruses in nature. However, linking viruses to their hosts remains a challenge.

02

Our solution

By leveraging a critical stage in the viral infection cycle, the translation of viral genes into proteins by the host cell, we aim to uncover hidden relationships between viruses and their hosts, providing a universal tool for virus-host pairing.

03

Effective plan

Our plan involves leveraging the most innovative biotechnological approach to link the nucleic acids of different virus-host combinations.

The VirHoX logo designer

The VirHox logo was created by Elena Rampazzo, a designer from Padova with no prior knowledge of virology. Starting from the project abstract, she formulated the current design.

“I wanted to represent the close relationship that takes shape between the virus and its host, not only by superimposing symbolic forms, but by creating interweaving between them“

The logo is made up of three parts: a circle to remember the diversity of viruses, which merges with a triangle that recalls the taxonomy of life, while an X acts as a glue to associate the other parts.


The VirHoX team

Virhox unites top experts from across Europe, dedicated to uncovering the complex dynamics between viruses, bacteria, and ribosomes. Our collaborative efforts aim to enhance scientific understanding and public health.

MEET the TEAM

Check our currently available positions

Join Us
Scroll to Top